ORGANIC-PHARMACEUTICALS LITERATURE

    • Schmidt, M. U., et al. "Electron Diffraction, X-Ray Powder Diffraction and Pair-Distribution- Function Analyses to Determine the Crystal Structures of Pigment Yellow 213, C23H21N5O9." Acta Crystallographica Section B: Structural Science, vol. 65, no. 2, pp. 189–99,, 2009, doi: 10.1107/S0108768109003759

    • Gorelik, T., et al. "Using Electron Diffraction to Solve the Crystal Structure of a Laked Azo Pigment." Crystal Growth and Design, vol. 9, no. 9, pp. 3898–903, 2009, doi: 10.1021/cg801099r

    • Gorelik, T., et al. "H-Bonding Schemes of Di-and Tri-p-Benzamides Assessed by a Combination of Electron Diffraction, X-Ray Powder Diffraction and Solid-State NMR." CrystEngComm, vol. 12, no. 6, pp. 1824–32, 2010, doi: 10.1039/b920569a

    • Kolb, U., et al. "Structural Characterization of Organics Using Manual and Automated Electron Diffraction." Polymer Reviews, vol. 50, no. 3, pp. 385–409, 2010, doi: 10.1080/15583724.2010.494238

    • Gorelik, T. E., et al. "Ab-Initio Crystal Structure Analysis and Refinement Approaches of Oligo p-Benzamides Based on Electron Diffraction Data." Acta Crystallographica Section B: Structural Science, vol. 68, no. 2, International Union of Crystallography, pp. 171–81, 2012, doi: 10.1107/S0108768112003138

    • Gorelik, T. E., et al. "Detecting Crystalline Nonequilibrium Phases on the Nanometer Scale." Crystal Growth and Design, vol. 12, no. 6, pp. 3239–42, 2012, doi: 10.1021/cg300377j

    • Virginia Altoe, et al. "Electron Microscopy Reveals Structure and Morphology of One Molecule Thin Organic Films", 2012, doi: https://doi.org/10.1021/nl203776n

    • Förster, C., et al. "Crystalline Non-Equilibrium Phase of a Cobalt(II) Complex with Tridentate Ligands." European Journal of Inorganic Chemistry, vol. no. 6, pp.920–24, 2015, doi: 10.1002/ejic.201403200

    • Van Genderen, E., et al. "Ab Initio Structure Determination of Nanocrystals of Organic Pharmaceutical Compounds by Electron Diffraction at Room Temperature Using a Timepix Quantum Area Direct Electron Detector." Acta Crystallographica Section A: Foundations and Advances, vol. 72, International Union of Crystallography, pp.236–42, 2016, doi: 10.1107/S2053273315022500

    • Gorelik, T. E., et al. "Crystal Structure of Disordered Nanocrystalline _II-Quinacridone Determined by Electron Diffraction." CrystEngComm, vol. 18, no. 4, Royal Society of Chemistry, pp. 529–35, 2016, doi: 10.1039/c5ce01855b

    • Wilke, M., et al. "The Crystallisation of Copper(II) Phenylphosphonates." Dalton Transactions, vol. 45, no. 43, Royal Society of Chemistry, pp. 17453–63, 2016, doi: 10.1039/c6dt02904c

    • Wang, Y., et al. "Elucidation of the Elusive Structure and Formula of the Active Pharmaceutical Ingredient Bismuth Subgallate by Continuous Rotation Electron Diffraction." Chemical Communications, vol. 53, no. 52, pp. 7018–21, 2017, doi: 10.1039/c7cc03180g

    • Das, P. P., et al. "Crystal Structures of Two Important Pharmaceuticals Solved by 3D Precession Electron Diffraction Tomography." Organic Process Research and Development, vol. 22, no. 10, American Chemical Society, pp. 1365–72, 2018, doi: 10.1021/acs.oprd.8b00149

    • Gruene, T., et al. "Rapid Structure Determination of Microcrystalline Molecular Compounds Using Electron Diffraction." Angewandte Chemie – International Edition, vol. 57, no. 50, pp. 16313–17, 2018, doi: 10.1002/anie.201811318

    • Jones, C. G., et al. "The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination." ACS Central Science, vol. 4, no. 11, pp. 1587–92, 2018, doi: 10.1021/acscentsci.8b00760

    • Kunde, T., et al. "Microcrystal Electron Diffraction (MicroED) for Small-Molecule Structure Determination." Angewandte Chemie – International Edition, vol. 58, no. 3,pp.666–68, 2019, doi: 10.1002/anie.201813215

    • Clabbers, M. T. B., et al. "Reducing Dynamical Electron Scattering Reveals Hydrogen Atoms." Acta Crystallographica Section A: Foundations and Advances, vol. 75, no. 1, International Union of Crystallography, pp. 82–93, 2019, doi: 10.1107/S2053273318013918

    • Jones, C. G., et al. "Characterization of Reactive Organometallic Species via MicroED." ACS Central Science, vol. 5, no. 9, pp. 1507–13, 2019, doi: 10.1021/acscentsci.9b00403

    • Andrusenko, I., et al. "The Crystal Structure of Orthocetamol Solved by 3D Electron Diffraction." Angewandte Chemie – International Edition, vol. 58, no. 32, pp.10919–22, 2019, doi: 10.1002/anie.201904564

    • Guzmán-Afonso, C., et al. "Understanding Hydrogen-Bonding Structures of Molecular Crystals via Electron and NMR Nanocrystallography." Nature Communications, vol. 10, no. 1, Springer US, pp. 1–10, 2019, doi: 10.1038/s41467-019-11469-2

    • Broadhurst, E. T., et al. "Polymorph Evolution during Crystal Growth Studied by 3D Electron Diffraction." IUCrJ, vol. 7, pp. 5–9, 2020, doi: 10.1107/S2052252519016105

    • Gemmi, M., et al. "A New Method Based on Electron Diffraction for Detecting Nanoparticles in Injectable Medicines." Journal of Pharmaceutical Sciences, vol. 109, no. 1, Elsevier Ltd, pp. 891–99, 2020, doi: 10.1016/j.xphs.2019.07.008

    • Iryna Andrusenko, et al. "A new olanzapine cocrystal obtained from volatile deep eutectic solvents and determined by 3D electron diffraction", Acta Cryst. . B76, 1036–1044, 2020, doi: 10.1107/S2052520620012779

    • Victoria Hamilton, et al. "Racemic Conglomerate Formation via Crystallization of Metaxalone from Volatile Deep Eutectic Solvents", Cryst. Growth Des. 20, 4731_4739, 2020, doi: 10.1021/acs.cgd.0c00497

    • Emma Danelius, et al. "MicroED in natural product and small molecule research", The Royal Society of Chemistry, 2020, doi: 10.1039/d0np00035c

    • Bo Wang, et al. "Absolute configuration determination of pharmaceutical crystalline powders by MicroED via chiral salt formation", 2022, doi: https://doi.org/10.1039/d2cc00221c

    • Nicole Hoefer, et al. "Crystal Structure Determination of Gramicidin by Microcrystal Electron Diffraction", 2022, doi: https://doi.org/10.1017/S1431927622004573

    • Tatiana E. Gorelik, et al. "Crystal structure of natural product argyrin-D determined by 3D electron diffraction", 2022, doi: https://doi.org/10.1039/D2CE00707J

    • Lightowler, et al. "Investigating polymorphism in small molecules using three-dimensional electron diffraction", 2022, doi: https://su.diva-portal.org/smash/record.jsf?pid=diva2%3A1685658

    • Laurence R. Doyle, et al. "MicroED characterization of a robust cationic σ-alkane complex stabilized by the [B(3,5-(SF5)2C6H3)4]− anion, via on-grid solid/gas single-crystal to single-crystal reactivity", 2022, doi: https://doi.org/10.1039/D2DT00335J

    • Vince M. Hipwell, et al. "Scale-Dependent Photosalience and Topotactic Reaction of Microcrystalline Benzylidenebutyrolactone Determined by Electron Microscopy and Electron Diffraction", 2022, doi: https://doi.org/10.1021/acs.cgd.1c01378

    • E. Mugnaioli, et al. "Strategies for structure solution of small-molecule organics by 3D ED using a small beam", 2022, doi: https://journals.iucr.org/a/issues/2021/a2/00/a59751/a59751.pdf

    • S. Plana-Ruiz, et al. "The crystal structure determination of an organic dye with triclinic symmetry by electron diffraction", 2022, doi: https://doi.org/10.1107/S0108767321095234

    • Darpandeep Aulakh, et al. "Retrospect and Prospect of Small Molecule Microcrystal Electron Diffraction for Pharmaceutical Industry", 2022, doi: https://journals.iucr.org/a/issues/2022/a1/00/a60899/a60899.pdf

    • Iryna Andrusenko, et al. "3D electron diffraction for structure determination of small-molecule nanocrystals: A possible breakthrough for the pharmaceutical industry", 2022, doi: https://doi.org/10.1002/wnan.1810

    • Christopher J. H. Smalley, et al. "A structure determination protocol based on combined analysis of 3D-ED data, powder XRD data, solid-state NMR data and DFT-D calculations reveals the structure of a new polymorph of l-tyrosine", 2022, doi: https://doi.org/10.1039/D1SC06467C

    • Shuting Li, et al. "Direct Structure determination from Spherulites using 3D Electron Diffraction", 2022, doi: https://doi.org/10.26434/chemrxiv-2022-jh1lx

    • Erik Svensson Grape, et al. "Structure of the active pharmaceutical ingredient bismuth subsalicylate", 2022, doi: https://doi.org/10.1038/s41467-022-29566-0

    • Erik Svensson Grape, et al. "Triple helix and rod structures of the antiseptic drug bibrocathol revealed by electron crystallography", 2022, doi: https://doi.org/10.1039/D2CC04209F

    • Iryna Andrusenko, et al. "True mol­ecular conformation and structure determination by three-dimensional electron diffraction of PAH by-products potentially useful for electronic applications·, 2022, doi: https://doi.org/10.1107/S205225252201154X

    • Iryna Andrusenko, et al. "Two New Organic Co-Crystals Based on Acetamidophenol Molecules", 2022, doi: https://doi.org/10.3390/sym14030431

    • Joseph Hitchen, et al. "Organic Cocrystals of TCNQ and TCNB Based on an Orthocetamol Backbone Solved by Three-Dimensional Electron Diffraction", 2023, doi: https://doi.org/10.1021/acs.cgd.1c01095

    • Kiyofumi Takaba, et al. "Comprehensive application of XFEL micro crystallography for novel organic compounds", 2023, doi: https://doi.org/10.26434/chemrxiv-2023-69p99

    • Tatiana E. Gorelik, et al. "Crystal structure of 9, 10-bis-((perchloro-phenyl)-ethynyl) anthracene determined from three-dimensional electron diffraction data", 2023, doi: https://doi.org/10.1515/zkri-2023-0009

    • Danelius E, et al. "MicroED as a powerful tool for structure determination of macrocyclic drug compounds directly from their powder formulations", 2023, doi: https://doi.org/10.1101/2023.07.31.551405

    • Joseph Hitchen, et al. "Organic Cocrystals of TCNQ and TCNB Based on an Orthocetamol Backbone Solved by Three-Dimensional Electron Diffraction", 2023, doi: https://doi.org/10.1021/acs.cgd.1c01095

    • Molly Lightowler, et al. "Phase identification and discovery of hidden crystal forms in a polycrystalline pharmaceutical sample using high-throughput 3D electron diffraction", 2023, doi: https://chemrxiv.org/engage/chemrxiv/article-details/6466d172a32ceeff2ddee872

    • Bu G1, et al. "Polymorphic Structure Determination of the Macrocyclic Drug Paritaprevir by MicroED", 2023, doi: https://doi.org/10.1101/2023.09.09.556999

    • Jessica E. Burch, et al. "Putting MicroED to the test: an unabridged account of the evaluation of 30 diverse pharma compounds", 2023, doi: https://chemrxiv.org/engage/chemrxiv/article-details/61670e747d3da50c42f692b9

    • Kunal Kumar Jha, et al. "Structures of Vitamin D derivatives by electron diffraction", 2023, doi: https://programme.conventus.de/en/mc-2023/posters/52cfbada-3556-4038-ab19-40980527ee74

    • Jieye Lin, et al. "Unraveling the Structure of Meclizine Dihydrochloride with MicroED", 2023, doi: https://doi.org/10.1101/2023.09.05.556418

    • Pedro Nunes, et al. "3D Electron Diffraction of Small Molecules on the MerlinEM Detector", 2023, doi: https://doi.org/10.1093/micmic/ozad067.511

    • Lorenza Romagnoli, et al. "4,4′-(Anthracene-9,10-diylbis(ethyne-2,1-diyl))bis(1-methyl-1-pyridinium) Lead Iodide C30H22N2Pb2I6: A Highly Luminescent, Chemically and Thermally Stable One-Dimensional Hybrid Iodoplumbate", 2023, doi: https://doi.org/10.1021/acs.chemmater.2c03798

    • Tatiana E. Gorelik, et al. "Analysis of diffuse scattering in electron diffraction data for the crystal structure determination of Pigment Orange 13, C32H24Cl2N8O2", 2023, doi: https://doi.org/10.1107/S2052520623000720

    • Shuting Li, et al. "Direct structure determination of vemurafenib polymorphism from compact spherulites using 3D electron diffraction", 2023, doi: https://doi.org/10.1038/s42004-022-00804-2

    • Jieye Lin1, et al. "Distinct Conformations of Mirabegron Determined by MicroED", 2023, doi: https://doi.org/10.1101/2023.06.28.546957

    • Emma Danelius, et al. "MicroED in drug discovery", 2023, doi: https://doi.org/10.1016/j.sbi.2023.102549

    • Kiyofumi Takaba, et al. "Structural resolution of a small organic molecule by serial X-ray free-electron laser and electron crystallography", 2023, doi: https://doi.org/10.1038/s41557-023-01162-9

    • Diptajyoti Gogoi, et al. "Structure Elucidation of Olanzapine Molecular Salts by Combining Mechanochemistry and Micro-Electron Diffraction", 2023, doi: https://doi.org/10.1021/acs.cgd.3c00432

    • Dr. Durga Prasad Karothu, et al. "The Elusive Structure of Levocetirizine Dihydrochloride Determined by Electron Diffraction", 2023, doi: https://doi.org/10.1002/anie.202303761

    • Bu, Guanhong Wieske, et al. "Simeprevir: The First Macrocyclic Drug Elucidated Ab Initio by MicroED", 2023, doi: https://www.diva-portal.org/smash/record.jsf?pid=diva2%3A1750553&dswid=-8778

    • Avital Wagner, et al. "Structure Determination of Biogenic Crystals Directly from 3D Electron Diffraction Data", 2024, doi: https://pubs.acs.org/doi/10.1021/acs.cgd.3c01290

    • Leung, Helen W, et al. "From formulation to structure: 3D electron diffraction for the structure solution of a new indomethacin polymorph from an amorphous solid dispersion", 2024, doi: https://doi.org/10.1107/S2052252524008121

    • Hidetomo Yokoo, et al. "Rapid Structure Determination of Ranitidine Hydrochloride API in Two Crystal Forms Using Microcrystal Electron Diffraction", 2024, doi: https://doi.org/10.1248/cpb.c23-00745

    • Agata Jeziorna, et al. "SCXRD, CSP-NMRX and microED in the quest for three elusive polymorphs of meloxicam", 2024, doi: https://doi.org/10.1107/S2052252524011898

    • Youwei Xu, et al. "Structure Determination and 3D ED/MicroED-Guided Synthesis of a New (S)-Ibuprofen–l-phenylalanine Co-Crystal", 2024, doi: https://doi.org/10.1021/acs.cgd.3c01391

    • Erik Svensson Grape, et al. "Brilliantly red: the structure of carmine", 2024, doi: https://doi.org/10.26434/chemrxiv-2024-30t84-v2

    • Emre Yörük, et al. "Electron diffraction unveils the 2D metal-radical framework of two molecule-based magnets", 2024, doi: https://doi.org/10.1039/D4QI02257B

    • Yaşar Krysiak, et al. "High Temperature Electron Diffraction on Organic Crystals: In Situ Crystal Structure Determination of Pigment Orange 34", 2024, doi: https://doi.org/10.1021/jacs.3c14800

    • Kaichao Wang, et al. "Large-Scale Synthesis of High-Purity Isoguanosine and Resolution of its Crystal Structure by Microcrystal Electron Diffraction", 2024, doi: https://doi.org/10.1002/open.202400141

    • Molly Lightowler, et al. "Phase Identification and Discovery of an Elusive Polymorph of Drug-Polymer Inclusion Complex Using Automated 3D Electron Diffraction", 2024, doi: https://doi.org/10.1002/anie.202317695

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