TEM Orientation Imaging - ASTAR

ASTAR device uses novel TEM based orientation mapping technique to characterize any material up to 1 nm scale based on collection of precession electron diffraction patterns (PED).
In combination with TOPSPIN acquisition of simultaneous orientation /phase /strain /STEM maps are possible

TEM Nanoscale Strain Mapping

Novel Automated Strain Mapping Solution for TEM/STEM (Patent pending) based on nanobeam precession diffraction patterns and STEM reference image acquisition. Precision up to 0.02% (200kV FEG) with spatial resolution < 2 nm (FEG TEM). In combination with TOPSPIN acquisition of simultaneous orientation /phase /strain /STEM maps are possible.

3D Precession diffraction tomography

3D diffraction tomography in combination with DigiSTAR and precession diffraction device enable automatic reconstruction of reciprocal cell of any material and solve any nanocrystalline structure.

Enhanced EELS & EDX spectroscopy

Beam Precession with DigiSTAR may enhance EELS & EDX signal reducing channeling effects. EELS quantification possible via TOPSPIN model based EELS quantification.


TOPSPIN is a digital STEM, beam Precession Electron Diffraction analytical Experimental framework offering a suite of beam precession imaging and advanced analytical experiments.

Analysis of amorphous materials

Electron Pair Distribution Function (e-PDF) is an electron diffraction based technique that allows to analyze local order in amorphous and nanocrystalline materials from diffuse or ring ED patterns.





Applications: April 1st May 31th 2021

Dr. Partha Pratim Das, Dr. Arturo Ponce-Pedraza, 
Dr. Enrico Mugnaioli, Dr. Stavros Nicolopoulos

Deadline for manuscript submissions: 15 August 2021

Our 3D precession electron diffraction work (combined with direct detection camera) on a very complex organic molecule (Linagliptin drug for Diabetes II desease) is selected as a cover page of the prestigious journal “Crystal Growth & Design”. Title “ Crystal Structure of Linagliptin Hemihydrate Hemiethanolate (C25H28N8O2)2(H2O)(C2H5OH) from 3D Electron Diffraction Data, Rietveld Refinement, and Density Functional Theory Optimization”
This is one of the largest structures solved with ED data in TEM. The structure contains 35 non H atoms in the molecule (there are 2 molecules in the asymmetric unit). More information on :

NanoMEGAS is partner of the European Network for Transmission Electron Microscopy with expertize in electron difffraction/crystallography techniques and TEM orientation imaging

Read more at :

ESTEEM3 – Enabling Science and Technology through European Electron Microscopy – is an EU funded project for electron microscopy, which aims at providing access to the leading European state-of-the-art electron microscopy research infrastructure. Facilitating and extending transnational access services of the most powerful atomic scale characterization techniques in advanced electron microscopy research to a wide range of academic and industrial research communities for the analysis and engineering of novel materials in physical, chemical and biological sciences.

ESTEEM3’s objective is to deliver access to users coming from a wider range of disciplines. Transnational Access (TA) to ESTEEM3 centers is obtained through a transparent, simple peer review process based on merit and scientific priorities. Optimum service to users is supported by Networking Activities (NA) and Joint Research Activities (JRA), which address key issues such as specimen preparation, data interpretation, treatment and automation through theory and simulation, and standardization of protocols and methodologies.


PICO 2022

08 to 12 May 2022
Kateel Vaalsbroek – Vaalsbroek – Netherlands


08 to 20 May 2022
School of TEM – Port Barcares – France


16th Multinational Congress on Microscopy (MCM)

04 to 09 September 2022
Brno, Czech Republic

M&M 2022 Portland

31 July 2022 to 04 August 2022
Portland, Oregon, USA

ECM33 Versailles

23 to 27 August 2022
Versailles, France


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